The insidious Mr. Negative poisons Cloak & Dagger against each other, as Spider-Man and his allies battle a deadly infestation in the thick of SPIDER-ISLAND! Ty and Tandy always balanced each other out, but the corrupting touch of Mr. Negative makes Cloak & Dagger fated enemies! Nick Spencer (SECRET AVENGERS, IRON MAN 2.0) and Emma Ríos (AMAZING SPIDER-MAN, OSBORN) take the fan-favorite duo in unbelievable new directions!