Deadpool clashes with the X-Men in adventures that give new meaning to the word "classic"! First, a bromance is rekindled as Deadpool and Cable - the Merc with the Mouth and the Soldier with the Shoulders - face a fight for the future! Then, learn the secret shared history of the Regeneratin' Degenerate and the Ragin' Cajun as Wade and Gambit take on one last job together! Plus: The Forbush Man's murder sparks fears that someone is targeting Marvel's funniest characters for death. Deadpool must act before someone bumps off Squirrel Girl, Rocket Raccoon, Groot, Ant-Man, Howard the Duck and...the Punisher?! And Deadpool takes on Halloween and Christmas!
Collecting DEADPOOL & CABLE: SPLIT SECOND #1-3, DEADPOOL VS. GAMBIT #1-5, DEADPOOL: TOO SOON? #1-4 and material from GWENPOOL SPECIAL #1 and GWENPOOL HOLIDAY SPECIAL: MERRY MIX-UP #1.